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The varieties of consequent enzymatic dysfunction resulting from these mutations include impaired binding of substrate and cofactor to the isozyme, blocked formation of a functional isozyme (deletion, nonsense mutation, or splice-junction alterations), and an unstable isozyme resulting in DHT deficiency due to a decreased conversion of testosterone to DHT (5)

Eur J Pharm Biopharm 132:94102 de Oliveira CP et al (2008) Prevention and reversion of nonalcoholic steatohepatitis in OB/OB mice by S -nitroso- N -acetylcysteine treatment

Unravelling the untapped pharmacological potential of plant molecules as inhibitors of BACE1: in silico explorations for Alzheimers disease

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Elegant work has examined the immunomodulatory impact of synovial tissue lactate in RA patients

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